doi: 10.15389/agrobiology.2013.2.40eng
UDC 636.4:636.064:[573.6.086.83+577.21]:577.175.322
BIOLOGICAL CHARACTERISTICS OF PIGS TRANSGENIC FOR HUMAN GROWTH HORMONE
L.K. Ernst1, N.A. Zinovieva1, N.A. Volkova1, A.Yu. Filimonov2, I.A. Ralkov1, I.V. Gusev1, G. Brem3
1All-Russian Research Institute of Animal Husbandry, Russian Academy of Agricultural Sciences,
pos. Dubrovitsy, Moscow Province, 142132 Russia,
e-mail: n_zinovieva@mail.ru;
2N.I. Pirogov Russian National Research Medical University,
1, ul. Ostrovityanova, Moscow, 117997 Russia,
e-mail: aleks_ariah@mail.ru;
3Institute of Animal Husbandry and Animal Welfare of the University of Veterinary Medicine,
Vienna A-1210, Austria,
e-mail: gottfried.brem@agrobiogen.de
Received January 15, 2013
The increase of growth hormone expression in pigs transgenic for WAP-hGH gene construct of F3 (non-pregnant and lactating sows) and F5 generations (young gilts in age of 5 and 9 months) was observed. The alteration of some biochemical characteristics of blood serum in transgenic pigs comparing to control animals was detected. The differences in correlation relationships between some biochemical characteristics of transgenic and control pigs were established.
Keywords: transgenic pigs, growth hormone, biochemical characteristics, correlation.
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